medicube EGF NAD+ Firming Serum – firming peptide serum

💗 EGF NAD+ Firming Serum – firming peptide serum with EGF and NAD+

Lightweight, everyday serum with 2.5 ppm sh-Oligopeptide-1 (EGF), 1 ppm NAD+, niacinamide and ectoin to care for fine lines, loss of firmness and dull, uneven skin appearance. It supports the overall effect of smoother, plumper and more elastic skin with multiple peptides, hyaluronic acid, adenosine and moisturizing ingredients.

✨ What does it do?

• Contains 2.5 ppm sh-Oligopeptide-1, a peptide communicated as EGF.
• Includes 1 ppm NAD+ in the formula.
• Supports a more even, radiant complexion with niacinamide.
• Helps maintain a more hydrated, comfortable skin feel with ectoin.
• Complements the firmness and smoothness-focused formula with various peptides.
• Supports the less noticeable appearance of fine lines with adenosine.
• Helps water retention with sodium hyaluronate.
• Contains collagen extract for moisturizing and conditioning.
• Completes the antioxidant formula with glutathione and berry fruit extracts.
• Lightweight, quickly layerable texture suitable for morning and evening use.
• Designed for both face and neck.
• Non-comedogenic and has passed primary skin irritation testing.

🧬 Key active ingredients

sh-Oligopeptide-1 – EGF 2.5 ppm

The formula contains 2.5 ppm sh-Oligopeptide-1.

This is a recombinant peptide, communicated in the cosmetics industry as EGF or an EGF-related peptide.

In the serum, it is part of the peptide system supporting smoother, more elastic, firmer and well-cared-for skin appearance.

Important: this is a cosmetic leave-on ingredient. The term “EGF” does not imply medical growth factor treatment or tissue regeneration.

NAD+ – 1 ppm

The formula contains 1 ppm Nicotinamide Adenine Dinucleotide, or NAD+.

NAD+ is a naturally occurring coenzyme, which medicube associates in this cosmetic formula with supporting fresher, more elastic and energetic skin appearance.

The 1 ppm concentration is specified in the finished product; this is not a medicinal or cellular-level “rejuvenation” treatment.

Niacinamide

The fourth ingredient in the INCI list, thus one of the formula’s more prominent components.

Supports a more even, radiant skin appearance, proper skin barrier function and the refined overall effect of pores.

Ectoin

An ingredient supporting skin moisture retention and comfort, particularly suitable for dehydrated or environmentally stressed skin routines.

Various peptides

Besides sh-Oligopeptide-1, the formula contains, among others, the following peptides:

• Acetyl Dipeptide-1 Cetyl Ester
• Palmitoyl Tripeptide-5
• Acetyl Hexapeptide-1
• Acetyl Octapeptide-3
• Copper Tripeptide-1
• Oligopeptide-3
• Oligopeptide-2
• Oligopeptide-1
• Hexapeptide-11

These complement the complex supporting smoother, firmer and more elastic skin appearance.

Adenosine

A cosmetic active used to support the less noticeable appearance of fine lines and the overall effect of more elastic skin.

Sodium Hyaluronate

The water-binding form of hyaluronic acid, supporting a more hydrated, softer and plumper skin feel.

Collagen Extract

The formula also contains collagen extract.

When applied topically, it primarily serves moisturizing, conditioning and film-forming roles – it is not intended for direct rebuilding of the skin’s own collagen.

Glutathione

An antioxidant ingredient complementing the formula that supports a brighter, fresher skin appearance.

Bacillus/Soybean Ferment Extract

Fermented soybean extract included as a skin conditioning ingredient in the formula.

📊 What did the manufacturer’s tests show?

According to medicube’s finished product tests, after two weeks of use:

• An 8.7% reduction was measured in the examined value of the visible appearance of smile lines,
• A 5.38% reduction in the visible appearance of neck lines.

The manufacturer also reports improvements in radiance indicators:

• forehead: +2.9%
• eye area: +2.2%
• around the mouth: +2.49%
• cheeks: +2.9%

These are manufacturer cosmetic test results, so individual results may vary.

🎯 Who is it recommended for?

It can be a particularly good choice for:

• caring for the appearance of fine lines,
• loss of firmness,
• skin that has lost elasticity,
• dull, tired-looking skin,
• uneven skin texture,
• dehydrated skin,
• refining the visible appearance of enlarged pores,
• regular care of the face and neck,
• if you want a slow-aging serum based on peptides and hydration without retinoids.

Medicube recommends it for all skin types and marks it as suitable for oily, combination, and sensitive skin.

🧴 How to use

After cleansing and toner, apply 2–3 drops to the face and neck, then gently spread and pat in.

Follow with a moisturiser.

Can be used both morning and evening.

Due to its light texture, it can be easily layered with other serums: apply the thinner formula first, then proceed to thicker textures.

💗 Why we love it

Because it is not built on a single trendy ingredient.

Alongside sh-Oligopeptide-1 communicated as EGF and NAD+, there is a truly serious peptide system, niacinamide, ectoin, hyaluronic acid, adenosine, ferment, and glutathione.

Thus, it can be an especially good choice for those who want to support hydration, radiance, and smoother skin texture alongside fine lines and loss of firmness, but not necessarily with a retinoid serum.

❓ Q&A

How much EGF does it contain?

Medicube specifies 2.5 ppm sh-Oligopeptide-1.

This peptide is communicated by the manufacturer as an EGF peptide.

Is the EGF here a genuine medical growth factor?

This is not a medical treatment.

The INCI lists a cosmetic peptide called sh-Oligopeptide-1, which is communicated as EGF. The product is a cosmetic skincare serum.

How much NAD+ is in it?

According to the manufacturer’s INCI, 1 ppm Nicotinamide Adenine Dinucleotide.

What does NAD+ mean?

Nicotinamide Adenine Dinucleotide is a coenzyme naturally present in the body.

In cosmetic products, it is used to support the skin’s fresher, more elastic, and cared-for appearance; it does not imply medicinal or cellular rejuvenation.

Are there only two peptides in it?

No. Besides the sh-Oligopeptide-1 communicated as EGF, it contains several other peptides, including Copper Tripeptide-1, Palmitoyl Tripeptide-5, and Acetyl Octapeptide-3.

Does it contain collagen?

Yes, Collagen Extract is listed in the INCI.

This acts as a moisturizing and conditioning ingredient; it does not mean that the collagen in the cream directly integrates into the skin’s own collagen network.

Does it contain hyaluronic acid?

Yes. It contains Sodium Hyaluronate.

Does it contain niacinamide?

Yes, and it is the fourth ingredient in the INCI, making it one of the formula’s key components.

Can it be used every day?

Yes. It can be used both morning and evening and does not require gradual introduction.

Is it suitable for sensitive skin?

Medicube recommends it for sensitive skin and communicates a primary skin irritation test.

Can it be used on acne-prone skin?

The finished product has also passed a non-comedogenic test, so it can be more easily incorporated into routines for oily and acne-prone skin.

It is not an acne treatment product.

Can it be used with vitamin C or retinol?

Yes. Medicube states it can be combined with vitamin C and retinol.

However, if you introduce several strong actives at once, it is advisable to add them separately to your routine to see how your skin tolerates them.

Can it be used on the neck as well as the face?

Yes. Medicube specifically markets it as a serum developed for the face and neck.