💚 Exosome Cica Serum – 60% centella water for calmer, more hydrated skin
The medicube Exosome Cica Serum – labelled as Exosome Cica Ampoule on some packaging – is a lightweight, watery serum primarily developed for the daily care of more sensitive, easily reddened, uneven-textured or compromised skin.
The formula is based on 60% Centella Asiatica leaf water, complemented by Centella Asiatica Leaf Vesicles – the key element of medicube’s Exosome Cica technology – additional centella components, 2% niacinamide, panthenol, allantoin, ectoin, tea tree, licorice and various hyaluronic acids.
Its light, fast-absorbing texture does not weigh down your routine, making it suitable for use both morning and evening, especially when you want to focus on a calmer, more hydrated and even skin feel.
✨ What does it do?
- Care with 60% centella leaf water: the formula is built on centella, not just supplemented with a small amount of plant extract.
- Contains Exosome Cica technology: Centella Asiatica Leaf Vesicles appear in the formula as vesicles derived from centella.
- Supports a more comfortable skin feel: panthenol, allantoin, ectoin and various centella components complement the light hydrating base.
- Helps create a more even, fresher complexion: 2% niacinamide supports tone and skin barrier care.
- Hydrates without heaviness: glycerin, betaine and three types of hyaluronic acid ensure moisture retention.
- Contains tea tree and licorice extracts: well suited to the daily routine of more problematic, easily destabilised skin.
- Easily layered: its watery ampoule texture absorbs quickly, making it comfortable under other serums and moisturisers.
🧬 Key ingredients
60% Centella Asiatica Leaf Water
Centella leaf water is the ingredient present in the highest proportion in the formula.
The light, watery base gives the serum a skin-conditioning and hydrating character, making it especially suitable for routines where comfort and light hydration are the main focus.
Exosome Cica – Centella Asiatica Leaf Vesicles
Listed in the INCI as Centella Asiatica Leaf Vesicles.
Medicube highlights this as Exosome Cica technology: microscopic vesicles derived from centella are used as a special component of the formula.
Centella complex
Besides the leaf water and Centella Leaf Vesicles, the formula contains several other centella components, including:
- Centella Asiatica Root Extract
- Asiaticoside
- Asiatic Acid
- Madecassoside
- Madecassic Acid
Together these provide the product’s intense cica character.
2% niacinamide
A versatile form of vitamin B3 that supports the skin’s natural protective barrier, hydration and a more even complexion.
Medicube specifically highlights the 2% concentration in this formula.
Panthenol + allantoin + ectoin
Three well-known hydrating and skin-conditioning ingredients that support a softer, more comfortable skin feel and complement the centella complex well.
Tea tree
Tea tree leaf water and tea tree extract are included in the formula. These plant ingredients are especially popular in routines for oily or more problematic skin.
Licorice + propolis
Glycyrrhiza Glabra Root Extract and Propolis Extract further complement the centella-tea tree formula as skin-conditioning ingredients.
Three types of hyaluronic acid
The formula contains Sodium Hyaluronate, Hyaluronic Acid and Hydrolyzed Hyaluronic Acid forms, which help maintain skin hydration and a softer, plumper feel.
🎯 Who is it recommended for?
Exosome Cica Serum may be a particularly good choice if:
- your skin is more sensitive or easily reddened,
- you often feel tightness or discomfort,
- your skin is more dehydrated,
- its texture is uneven or rougher,
- you are looking for a light serum without a rich cream-like feel,
- you want centella-based skincare,
- you seek a hydrating serum that layers well even on more problematic, oilier skin.
Medicube recommends it for all skin types.
🧴 Texture and place in your routine
A very light, watery ampoule-serum that absorbs quickly and does not leave a heavy, sticky layer.
After cleansing and toner, apply an appropriate amount evenly to the face, then gently pat in.
Follow with moisturiser.
Medicube recommends both morning and evening use.
💚 Why do we love it?
Because this is not a “cica serum” where centella only appears near the end of the ingredient list.
The formula is built on 60% centella leaf water, complemented by further centella components, Exosome Cica, panthenol, allantoin, ectoin, tea tree, licorice and hyaluronic acids.
At the same time, it remains very light and easily layered, making it especially suitable for those seeking a fresh, watery, everyday formula instead of a richer, oilier soothing serum.
The 2% niacinamide adds an extra tone- and barrier-care dimension, so it is interesting not only when the skin has lost comfort.
❓ Q&A
What does Exosome Cica mean?
Medicube uses centella-derived vesicles in this formula, listed in the INCI as Centella Asiatica Leaf Vesicles.
The brand calls this Exosome Cica technology.
How much centella does it contain?
The formula is based on 60% Centella Asiatica Leaf Water, and also contains several other centella-derived ingredients such as madecassoside, asiaticoside, asiatic acid and madecassic acid.
Can it be used morning and evening?
Yes. Medicube recommends twice daily use, both morning and evening.
Is it more of a hydrating or soothing serum?
Both. The high centella content, panthenol, allantoin and ectoin primarily support a more comfortable skin feel, while glycerin, betaine and hyaluronic acids provide a hydrating background.
Can it be used on oilier skin?
Yes. Its watery, light texture fits well into routines for combination and oilier skin, especially if you dislike heavy, creamy serums.
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